Desierto is a Member of the Expert Group of the United Nations Working Group on the Right to Development, Resource Expert for the Association of Southeast Asian Nations (ASEAN), former Director of Studies and Faculty at the Hague Academy of International Law, President of the Friends of the Hague Academy Foundation, and Philippines Focal Point for the International Criminal Court Bar Association. She is active as international counsel at matters successfully litigated at the Permanent Court of Arbitration, the UN Human Rights Committee, the Philippine Supreme Court and Southeast Asian agencies, and was appointed by the Philippine Supreme Court as Professor of International Law and Human Rights at the Philippines Judicial Academy. Desierto serves on the editorial and/or scientific advisory boards of the European Journal of International Law (and Editor of its leading international law blog EJIL:Talk!), Journal of World Investment and Trade, International Law Studies, and various Asian international law journals. Desierto previously taught as tenure-track/tenured law faculty at the University of the Philippines, Peking University School of Transnational Law in China, and the University of Hawaii Richardson School of Law. She is a recipient of faculty fellowships at Stanford University's Center for Advanced Studies in the Behavioral Sciences (CASBS) and the Stanford Center for Human Rights and International Justice, the Max Planck Institute for Comparative Public Law and International Law in Heidelberg, the Humboldt-Potsdam-Berlin Senior Fellowship, the East-West Center in Honolulu, the Grotius Fellowship at University of Michigan Law School, and the National University of Singapore's Asian Law Institute Fellowship. Desierto served as Visiting Professor at the University of Paris-Nanterre X Faculty of Law, the University of the Philippines College of Law Graduate Program at Bonifacio Global City, and the University of Navarre Faculty of Law in Spain.